RazuAd uses a Q Exactive Plus Orbitrap instrument that features fast high-energy collision-induced dissociation peptide fragmentation because of parallel filling and detection modes. The image current from the detector is processed by an “enhanced Fourier Transformation” algorithm, doubling mass spectrometric resolution. Together with almost instantaneous isolation and fragmentation, the instrument achieves overall cycle times of 1 s for a top10 higher energy collisional dissociation method. More than 2500 proteins can be identified in standard 90-min gradients using tryptic digests.
We can provide the following analyses for your samples:
- Peptide Mapping
- In Gel Digest
- Intact Mass with accurate mass within <1 ppm with internal standard
- Full Scan MS
- Selection Ion Monitoring (SIM)
- Parallel Reaction Monitoring (PRM)
- HPLC Method Development
- Establish Fit-for-Purpose Assays
- Identification of Post-Translational Modifications (PTM’s)